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July 17, 2013

Omega 3 fatty acids and prostate cancer risk

At a Glance

A recently published study on omega 3 fatty acids has generated negative headlines worldwide causing consumers to question the safety and health benefits of consuming fish and fish oil supplements. Many health professionals and nutrition experts have been quick to respond with refuting analyses and firm rebuttals.

Read more about this research below.

A recent study published in the Journal of the National Cancer Institute states that eating fatty fish and taking fish oil supplements may significantly increase the risk of prostate cancer.

There are numerous reasons to be critical of the conclusions presented in this study. First it is important to note that this study was not specifically designed to examine the relationship between dietary omega-3 fatty acids and prostate cancer. The results of this single analysis contradict dozens of others (even some by the same researchers) among thousands of published papers on the benefits of consuming fish and fish oil. Many experts have also questioned the relevance or validity of several of the statistical methods used in these analyses. In addition; the researchers themselves understand that this type of study cannot prove cause and effect, and often times these types of studies tend to raise more questions than are answered.

For a better understanding of this study please see the links provided. We hope this information will help provide you with the knowledge to make an informed decision about consuming fatty fish and fish oil supplements.

Global Organization for EPA and DHA Omega-3s (2013). Omega-3s and Prostate Cancer Risk [Peer commentary on the paper “Plasma Phospholipid Fatty Acids and Prostate Cancer Risk in the SELECT Trial” by Brasky T.M. et al, 2013, JNCI, doi:10.1093/jnci/djt174.]
http://us1.campaign-archive1.com/?u=4ae075406cd789efec4e9ff09&id=6f3dc7a018&e=1515e32d26

Council for Responsible Nutrition: CRN Says New Study On Omega-3 Conclusions Are Overblown. http://crnusa.org/CRNPR13-Omega3071113.html

Theodore M Brasky et al. Plasma Phospholipid Fatty Acids and Prostate Cancer Risk in the SELECT Trial.
J Natl Cancer Inst 2013 : djt174v1-djt174.

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July 3, 2013

Higher fruit and vegetable intake is associated with a lower mortality rate

At a Glance

It is well known that fruits and vegetables are important for health. A new study provides evidence that low fruit and vegetable intake may result in decreased survival and increased mortality rates.

Read more about this research below.

Many observational and epidemiological studies have shown a solid relationship between increased fruit and vegetable (FV) intake and better health outcomes. However, the association between FV intake and overall mortality has seldom been studied in large cohort studies.

In a new study published in the American Journal of Clinical Nutrition, researchers examined the dose-response relationship between dietary FV intake and mortality as it relates to both time and rate. The participants included 71,706 Swedish adults aged 45-83 years. Fruit and vegetable intake was recorded using self-administered questionnaires.

During the 13 years of follow-up 11,439 deaths occurred in this population. Researchers found that in comparison to those that consumed 5 servings of FV/day, lower FV intakes were associated with shorter survival and higher mortality rates in a dose dependent manner. Compared to adults that ate 5 servings FV/day, adults who never consumed FV lived 3 years shorter and had a 53% higher mortality rate. When fruits and vegetables were considered separately, people consuming at least 3 servings of vegetables per day lived 32 months longer than those who never consumed vegetables. Those who never ate fruit lived 19 months shorter than those that ate at least 1 serving of fruit per day.

The findings of this study confirm the previously known benefits of eating fruits and vegetables and show that consuming less than 5 servings/day is associated with a dose-dependent decrease in survival and an increase in mortality rates.

Andrea Bellavia et al. Fruit and vegetable consumption and all-cause mortality: a dose-response analysis First published June 26, 2013, doi: 10.3945/ajcn.112.056119 Am J Clin Nutr August 2013 ajcn.056119

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July 3, 2013

Higher fruit and vegetable intake is associated with a lower mortality rate

At a Glance

June 26, 2013

Higher CoEnzyme Q10 and vitamin B6 levels may be associated with a reduced risk of cardiovascular disease

At a Glance

In a recent study, researchers discovered a significant correlation between healthy plasma levels of coenzyme Q10 and vitamin B-6 and a reduced risk of coronary artery disease.

Read more about this research below.

Cardiovascular diseases are the leading cause of death worldwide, accounting for nearly 30% of all deaths. It is estimated that by 2030, over 23 million people will die from cardiovascular diseases annually.

In a new study published in Nutrition Research, scientists investigated the possible relationship between plasma levels of CoEnzyme Q10 and vitamin B6 and the risk of coronary artery disease (CAD). Study participants included 134 adults, 45 with at least 50% stenosis (blockage) of one major coronary artery. The control group (n=89) had normal blood biochemistry and were free of CAD. Researchers measured the plasma concentrations of CoQ10, vitamin B6 and lipid profiles of each participant.

Individuals with CAD were found to have significantly lower plasma CoQ10 and Vitamin B6 compared to the control group. Even after adjusting for other CAD risk factors, subjects with higher CoQ10 plasma concentration had a significantly lower risk of CAD. Higher plasma vitamin B6 concentration also related to a significantly lower risk of CAD, but the relationship was less significant after adjusting for other CAD risk factors.

This observational study suggests that there may be a significant correlation between the plasma levels of CoQ10 and Vitamin B6 and the risk of cardiovascular disease. The researchers state that further research should be conducted to examine the benefits of supplementing CoQ10 in combination with Vitamin B6 to CAD patients, especially if their CoQ10 levels are below normal levels. It should also be noted that Statin drugs, which are commonly prescribed to CAD patients and those at risk, are known to lower plasma CoQ10 levels.

Bor-Jen Lee et al. A significant correlation between the plasma levels of coenzyme Q10 and vitamin B-6 and a reduced risk of coronary artery disease. Nutrition Research Volume 32, Issue 10, Pages 751-756, October 2012.